Once inside the cell, the acidic conditions in the endosome cause two events to happen: First, part of the hemagglutinin protein fuses the viral envelope with the vacuole's membrane, then the M2 ion channel allows protons to move through the viral envelope and acidify the core of the virus, which causes the core to disassemble and release the viral RNA and core proteins.  The viral RNA (vRNA) molecules, accessory proteins and RNA-dependent RNA polymerase are then released into the cytoplasm (Stage 2).  The M2 ion channel is blocked by amantadine drugs, preventing infection. 
Drinking lots of fluids and using salt water gargles (made by combining a cup of warm water and a teaspoon of salt) can often be helpful for easing the pain of a sore throat . Over-the-counter pain relievers and medicated lozenges and gargles can also temporarily soothe a sore throat . Get your doctor's approval before using any medications, including over-the-counter drugs, and don't use lozenges or gargles for more than a few days. The medications could mask signs of strep throat , a bacterial infection that should be treated with antibiotics .
The best treatment for influenza infections in humans is prevention by vaccination. Work by several laboratories has produced vaccines . The first H1N1 vaccine released in early October 2009 was a nasal spray vaccine that was approved for use in healthy individuals ages 2-49. However, the use of nasal spray has not been recommended since 2016. The injectable vaccine, made from killed H1N1, became available in the second week of Oct. 2009. This vaccine was approved for use in ages 6 months to the elderly, including pregnant females. Both of these vaccines were approved by the CDC only after they had conducted clinical trials to prove that the vaccines were safe and effective. A new influenza vaccine preparation is the intradermal (trivalent) vaccine is available; it works like the shot except the administration is less painful. It is approved for ages 18-64 years.