Steroid bodyforum

HRT, consisting of systemic treatment with estrogen alone or in combination with a progestogen, has well-documented and considerable beneficial effects on the skin of postmenopausal women. [55] [56] These benefits include increased skin collagen content, skin thickness and elasticity, and skin hydration and surface lipids. [55] [56] Topical estrogen has been found to have similar beneficial effects on the skin. [55] In addition, a study has found that topical 2% progesterone cream significantly increases skin elasticity and firmness and observably decreases wrinkles in peri- and postmenopausal women. [56] Skin hydration and surface lipids, on the other hand, did not significantly change with topical progesterone. [56] These findings suggest that progesterone, like estrogen, also has beneficial effects on the skin, and may be independently protective against skin aging. [56]

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