Steroid dose for acute bronchitis

Caveats: The two RCTs, even when combined, are small and concrete conclusions would be premature, thus these data, while they represent the best currently available evidence, should be considered preliminary. In addition both studies were undertaken during the early and mid-1980’s and it is possible that when combined with more advanced supportive care modalities, or lung protective strategies, the intervention may be more effective. In addition, the trials studied different patient populations with one (Bernard 1987) examining patients with ARDS and the other (Weigelt 1985) examining patients with ALI. There was also significant heterogeneity between the two studies (I 2 = %).

SS among patients who received corticosteroids (35%) was significantly higher than in patients who did not receive corticosteroids (23%; P  = ) (Fig. 1 ). However, there were no significant differences in SS between steroid groups in any particular diagnosis subgroup, including those with AI-ALF (32% versus 20%, respectively, P  = ). In addition, reassignment of etiology based on a histological diagnosis of AI-ALF also yielded no difference (26% in those who received corticosteroids and 21% in those who did not ( P  = ).

In an attack of several days' duration prior to starting therapy, a longer course of treatment may be necessary. In such patients, added interventions to prevent NSAID gastropathy (eg, use of a proton pump inhibitor) may be of benefit, particularly in patients at increased risk due to advanced age or to a prior history of ulcer disease or gastrointestinal bleeding. (See "NSAIDs (including aspirin): Primary prevention of gastroduodenal toxicity" and "NSAIDs (including aspirin): Secondary prevention of gastroduodenal toxicity" .)

If you have questions about any of the clinical pathways or about the process of creating a clinical pathway please  contact us .

©2017 by Children's Hospital of Philadelphia, all rights reserved.
Use of this site is subject to the  Terms of Use .

The clinical pathways are based upon publicly available medical evidence and/or a consensus of medical practitioners at The Children’s Hospital of Philadelphia (“CHOP”) and are current at the time of publication. These clinical pathways are intended to be a guide for practitioners and may need to be adapted for each specific patient based on the practitioner’s professional judgment, consideration of any unique circumstances, the needs of each patient and their family, and/or the availability of various resources at the health care institution where the patient is located.

Accordingly, these clinical pathways are not intended to constitute medical advice or treatment, or to create a doctor-patient relationship between/among The Children’s Hospital of Philadelphia (“CHOP”), its physicians and the individual patients in question. CHOP does not represent or warrant that the clinical pathways are in every respect accurate or complete, or that one or more of them apply to a particular patient or medical condition. CHOP is not responsible for any errors or omissions in the clinical pathways, or for any outcomes a patient might experience where a clinician consulted one or more such pathways in connection with providing care for that patient.

Steroid dose for acute bronchitis

steroid dose for acute bronchitis

If you have questions about any of the clinical pathways or about the process of creating a clinical pathway please  contact us .

©2017 by Children's Hospital of Philadelphia, all rights reserved.
Use of this site is subject to the  Terms of Use .

The clinical pathways are based upon publicly available medical evidence and/or a consensus of medical practitioners at The Children’s Hospital of Philadelphia (“CHOP”) and are current at the time of publication. These clinical pathways are intended to be a guide for practitioners and may need to be adapted for each specific patient based on the practitioner’s professional judgment, consideration of any unique circumstances, the needs of each patient and their family, and/or the availability of various resources at the health care institution where the patient is located.

Accordingly, these clinical pathways are not intended to constitute medical advice or treatment, or to create a doctor-patient relationship between/among The Children’s Hospital of Philadelphia (“CHOP”), its physicians and the individual patients in question. CHOP does not represent or warrant that the clinical pathways are in every respect accurate or complete, or that one or more of them apply to a particular patient or medical condition. CHOP is not responsible for any errors or omissions in the clinical pathways, or for any outcomes a patient might experience where a clinician consulted one or more such pathways in connection with providing care for that patient.

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