As an example, should you choose to run a cycle that includes both Dianabol and Anavar, you will need to be extremely careful when it comes to overlapping them. The two are both hepatotoxic, which means they will cause liver damage. You will need to consider this carefully when it comes to choosing cycle lengths. If you take Dianabol for four weeks at the beginning of your cycle, then make the switch to Anavar, you should limit your Anavar use to four weeks, as well. This reduces your entire cycle time to eight weeks, which helps to alleviate some of the risk of liver damage.
Of concern to any user of Winstrol during a cycle should be its intoxicating effect on the liver . The drug is a 17aa structured steroid , meaning it has been structured in a way which allows it to be orally bio-available, yet this has the negative effect of making Winstrol potentially harmful to the liver. It is therefore paramount the duration of a Winstrol cycle is limited, the dose of the drug is not excessive, the user does not stack it with other hepatotoxic compounds, does not drink alcohol whilst on cycle, and does not use Winstrol if they have an underlying medical condition which effects the livers health. There are supplements available which also help protect the liver (Milk Thistle, Liv-52 etc), and these would be advisable during any Winstrol cycle .
As previously noted, cholesterol levels can change when oral steroids are used, even for short periods. Recent research has pointed the finger at cholesterol as being one of the most important steroid related side effects bodybuilders want to avoid. The thickening of the blood (red blood count RBC), artery plaque, high blood pressure, high LDL and low HDL can and will lead to coronary heart disease (CHD) if adequate precautions aren’t taken. It is thus advised; all oral steroids are taken for cycles of 6-8 weeks and no longer. Support supplements are also advised, these include: Curcumin, Citrus Bergamot, Vitamin K2, Omega-3.